DETECTION OF VASOPRESSIN MESSENGER-RNA IN THE NEUROINTERMEDIATE LOBE OF THE RAT PITUITARY

被引:29
作者
MCCABE, JT
LEHMANN, E
CHASTRETTE, N
HANZE, J
LANG, RE
GANTEN, D
PFAFF, DW
机构
[1] ROCKEFELLER UNIV, NEUROBIOL & BEHAV LAB, NEW YORK, NY 10021 USA
[2] UNIV HEIDELBERG, DEPT PHARMACOL, W-6900 HEIDELBERG, GERMANY
[3] UNIV HEIDELBERG, INST HIGH BLOOD PRESSURE RES, W-6900 HEIDELBERG, GERMANY
来源
MOLECULAR BRAIN RESEARCH | 1990年 / 8卷 / 04期
关键词
Antidiuretic hormone; Gene expression; Hypothalamus; mRNA; Neurointermediate lobe; Nucleic acid hybridization; Posterior pituitary; Vasopressin;
D O I
10.1016/0169-328X(90)90046-G
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A messenger ribonucleic acid (mRNA) homologous to the transcript that encodes vasopressin (VP) was detected in the neurointermediate lobe (NIL) of the rat pituitary. The abundance of this transcript is approximately 1/100th the amount detected in the hypothalamus. In rats drinking 2% naCl-water for 0, 2, 4, or 10 days, or for 10 days and then tap water for 14 days, the levels of VP mRNA in the NIL were altered in a fashion that paralleled changes in the hypothalamus. © 1990.
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页码:325 / 329
页数:5
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