The MHC: relationship between linkage and function

被引：35

作者：

Trowsdale, John ^{[1
]}

Powis, Stephen H. ^{[1
]}

机构：

[1] Imperial Canc Res Fund, Human Immunogenet Lab, Lincolns Inn Fields, London WC2A 3PX, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1992年 / 2卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(05)80163-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

It is intriguing that several genes with associated functions, including all of class I and class II genes, as well as some genes affecting antigen presentation of both class I and class II pathways, are linked in the MHC. Recent observations have led to speculation that there may be a functional explanation for keeping these related genes together.

引用

页码：492 / 497

页数：6

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