COMPUTER-SIMULATION OF REENTRY SOURCES IN MYOCARDIUM IN 2 AND 3 DIMENSIONS

被引:55
作者
PANFILOV, AV
HOLDEN, AV
机构
[1] UNIV LEEDS, DEPT PHYSIOL, LEEDS LS2 9JT, W YORKSHIRE, ENGLAND
[2] UNIV UTAH, DEPT MATH, SALT LAKE CITY, UT 84112 USA
基金
英国惠康基金;
关键词
D O I
10.1006/jtbi.1993.1055
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Re-entry in a simple model of cardiac muscle is examined. The properties of vortices in two dimensions are studied at different values of the ratio of the action potential duration to its rise time. The vortex changes from stationary to non-stationary rotation as the action potential duration is increased. A test for identifying nonstationary rotation from monophasic action potential recordings at a single site in cardiac tissue is proposed. In three dimensions re-entry of the scroll ring type is examined. Contraction of the scroll ring and its vertical drift occurs in this model. The drift velocities are shown to depend inversely on the scroll ring radius. The dependence of these drift velocities on re-entry cycle length is estimated for cardiac tissue. © 1993 by Academic Press.
引用
收藏
页码:271 / 285
页数:15
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