STEREOCHEMISTRY AND PHYSIOLOGICAL SIGNIFICANCE OF HYDROXYLATION OF VITAMIN-D SIDE-CHAIN

被引：6

作者：

IKEKAWA, N

机构：

[1] Iwaki Meisei University, Iwaki, Fukushima

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 09期

关键词：

D O I：

10.1016/S0960-894X(00)80106-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Stereochemical aspect of side chain hydroxylation (C-23, C-24, and/or C-26 positions) of vitamin D3 is described. The effect of the configuration of hydroxy group on biological activities is emphasized. Stereochemistry of vitamin D hydroxylation is compared with that of other natural hydroxylated steroids. Conformation of steroid side chain is also discussed

引用

页码：1789 / 1794

页数：6