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POSSIBLE ASSOCIATION OF C-HARVEY-RAS-1 (HRAS-1) MARKER WITH AUTISM

被引：49
作者：
HERAULT, J
PERROT, A
BARTHELEMY, C
BUCHLER, M
CHERPI, C
LEBOYER, M
SAUVAGE, D
LELORD, G
MALLET, J
MUH, JP
机构：
[1] CHR UNIV BRETONNEAU,INSERM,U316,UNITE NERVOUS SYST FETUS CHILD,F-37044 TOURS,FRANCE
[2] CNRS,UPR 23,F-91198 GIF SUR YVETTE,FRANCE
来源：
PSYCHIATRY RESEARCH | 1993年 / 46卷 / 03期
关键词：
CHILD PSYCHIATRY; GENETICS; INFANTILE AUTISM; POLYMORPHISM;
D O I：
10.1016/0165-1781(93)90094-W
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
We tested for an association between autism and genes coding for enzymes involved in monoaminergic metabolism and for a linked marker, c-Harvey-Ras-1 (HRAS 1), using restriction fragment length polymorphisms. We did not find evidence of an association between autism and genes coding for tyrosine hydroxylase, dopamine-beta-hydroxylase (DBH), and tryptophan hydroxylase. However, we report a positive association between autism and the locus containing the gene for HRAS-1.
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页码：261 / 267
页数：7
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