ABSORPTION OF IRON FROM FERRIC HYDROXYPYRANONE COMPLEXES

被引：29

作者：

MAXTON, DG ^{[1
]}

THOMPSON, RPH ^{[1
]}

HIDER, RC ^{[1
]}

机构：

[1] UNIV LONDON KINGS COLL, DEPT PHARM, LONDON SW3 6OX, ENGLAND

来源：

BRITISH JOURNAL OF NUTRITION | 1994年 / 71卷 / 02期

关键词：

IRON; FERRIC HYDROXYPYRANONE; ANEMIA; MAN;

D O I：

10.1079/BJN19940127

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The absorption of Fe-59 from preparations of FeSO4 and the ferric hydroxypyranone complexes maltol and ethyl maltol was studied by whole-body counting in normal subjects and patients with Fe deficiency. Fe in the Fe3+ complexes was in general absorbed almost as well as Fe2+. It is concluded that the absorption of Fe3+ from hydroxypyranone complexes is much greater than that from simple Fe3+ salts; this may prove an efficient and less toxic form of Fe for the treatment of deficiency.

引用

页码：203 / 207

页数：5

共 18 条

[1] EFFECTS OF THE PYRONES, MALTOL AND ETHYL MALTOL, ON IRON-ABSORPTION FROM THE RAT SMALL-INTESTINE [J].

BARRAND, MA ;

CALLINGHAM, BA ;

HIDER, RC .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1987, 39 (03) :203-211

[2] A SMALL-DOSE IRON TOLERANCE-TEST AS AN INDICATOR OF MILD IRON-DEFICIENCY [J].

CROSBY, WH ;

ONEILCUTTING, MA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1984, 251 (15) :1986-1987

[3]

DIETZFELBINGER H, 1987, ARZNEIMITTEL-FORSCH, V37-1, P107

[4]

FORTH W, 1987, ARZNEIMITTEL-FORSCH, V37-1, P96

[5] IRON-ABSORPTION [J].

FORTH, W ;

RUMMEL, W .

PHYSIOLOGICAL REVIEWS, 1973, 53 (03) :724-792

[6]

GERARD C, 1980, J CHEM RES-S, P314

[7]

HALLBERG L, 1966, ACTA MED SCAND, VS, P3

[8]

HEINRICH HC, 1987, ARZNEIMITTELFORSCH, V37-1, P105

[9]

Hider R C, 1991, Prog Med Chem, V28, P41, DOI 10.1016/S0079-6468(08)70363-1

[10] IRON FORTIFICATION OF INFANT CEREALS - A PROPOSAL FOR THE USE OF FERROUS FUMARATE OR FERROUS SUCCINATE [J].

HURRELL, RF ;

FURNISS, DE ;

BURRI, J ;

WHITTAKER, P ;

LYNCH, SR ;

COOK, JD .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1989, 49 (06) :1274-1282

← 1 2 →