CONJUGQTE ADDITION OF HYDROGEN CYANIDE TO 5BETA-HYDROXY-10BETA-METHYL-1(9)-OCTAL-2-ONE . A REINVESTIGATION

被引：6

作者：

RAO, PN

BURDETT, JE

机构：

[1] Division of Biological Growth and Development, Department of Organic Chemistry, Southwest Foundation for Research and Education, San Antonio

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1969年 / 34卷 / 04期

关键词：

D O I：

10.1021/jo01256a068

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conjugate addition of hydrogen cyanide to 5β-hydroxy-10β-methyl-1(9)-octal-2-one (2) gave a mixture of two ketonitriles (4a) and (4b). From unequivocal chemical studies and nmr spectral data the major product with mp 158-159° (4b) was assigned the trans configuration and the minor product with mp 189-190° (4a) was assigned the cis configuration. Earlier assignments of configuration of these compounds are revised. © 1969, American Chemical Society. All rights reserved.

引用

页码：1090 / &

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (02) :325-&

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