UNUSUAL REACTIONS OF SECONDARY AMINO-ACIDS WITH TRIFLUOROACETIC-ANHYDRIDE - A NOVEL ACCESS TO ALPHA-TRIFLUOROMETHYLATED ACYLOINS

被引：22

作者：

KAWASE, M

机构：

[1] Faculty of Pharmaceutical Sciences, Josai University, Sakado-shi, Saitama, 350-02

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 01期

关键词：

D O I：

10.1016/0040-4039(94)88187-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new fragmentation reaction of secondary alpha-amino acids with trifluoroacetic anhydride under Dakin-West reaction conditions proceeds through oxazolium salt intermediates followed by ring cleavage to form alpha-trifluoromethylated acyloins in good yields.

引用

收藏

页码：149 / 152

页数：4

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