DIFFERENTIAL IMMUNOCYTOCHEMICAL LOCALIZATION OF GABA(A) RECEPTOR GAMMA(1) AND RECEPTOR GAMMA(2) SUBUNITS IN THE RAT-BRAIN

被引：14

作者：

ARAKI, T

KIYAMA, H

MAENO, H

TOHYAMA, M

机构：

[1] Department of Anatomy and Neuroscience, Osaka University Medical School, Suita-shi, Osaka, 565

来源：

MOLECULAR BRAIN RESEARCH | 1993年 / 20卷 / 03期

关键词：

POLYCLONAL ANTIBODY; LIGHT MICROSCOPY; OLFACTORY BULB; HIPPOCAMPUS; CEREBELLUM;

D O I：

10.1016/0169-328X(93)90050-Y

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Subunit-specific polyclonal antisera against the GABA(A) receptor gamma1 and gamma2 subunits were raised in rabbits and used for immunoblotting and immunocytochemistry of the rat brain. Each subunit protein was differentially distributed even in the region like cerebellar cortex where mRNAs of both subunits were distributed in the same manner. This may indicate that GABA(A) receptor gamma1 and gamma2 subunit proteins are subject to a subunit-specific subcellular sorting mechanism.

引用

页码：263 / 266

页数：4

共 29 条

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