SAMARIUM DIIODIDE MEDIATED ALKYLATION OF SATURATED HETEROCYCLES ALPHA TO NITROGEN

被引：23

作者：

BOOTH, SE ^{[1
]}

BENNECHE, T ^{[1
]}

UNDHEIM, K ^{[1
]}

机构：

[1] UNIV OSLO,DEPT CHEM,N-0315 OSLO,NORWAY

来源：

TETRAHEDRON | 1995年 / 51卷 / 12期

关键词：

D O I：

10.1016/0040-4020(95)00081-I

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for alpha-alkylation of saturated 5-, 6-, 7- and and 8-membered aza-heterocycles is described. The auxiliary is an o-iodobenzyl group attached at the nitrogen. A radical introduced in the o-position is transferred to the amine alpha-position which subsequently leads to an addition reaction with pentan-3-one.

引用

页码：3665 / 3674

页数：10

共 23 条

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