STUDIES OF THE INDUCIBILITY OF P450-1A IN PERCH FROM THE PCB-CONTAMINATED LAKE-JARNSJON IN SWEDEN

被引：29

作者：

FORLIN, L

CELANDER, M

机构：

[1] Department of Zoophysiology, University of Göteborg, S-41390 Göteborg

来源：

MARINE ENVIRONMENTAL RESEARCH | 1995年 / 39卷 / 1-4期

关键词：

D O I：

10.1016/0141-1136(94)00029-O

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Comparatively low levels of hepatic EROD activities were observed in feral perch caught in Lake Jarnsjon, heavily contaminated with polychlorinated biphenyls (PCBs) when compared to reference sites. On the other hand rainbow trout, caged in Lake Jarnsjon, exhibited elevated EROD activities, P450 1A1 protein and CYP1A1 mRNA levels. The feral perch from the PCB area were non-responsive towards model P450 IA system inducers. These results suggest a possible pollutant-induced suppression or inactivation of the P450 IA system in feral perch in Lake Jarnsjon.

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页码：85 / 88

页数：4

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