SYNTHESIS OF (E)-2,6-DIMETHYL-6-HYDROXYOCTA-2,7-DIENOIC ACID AND THE CORRESPONDING AMIDE (ACACIALACTAM) IN OPTICALLY-ACTIVE FORM

被引：10

作者：

CARDA, M ^{[1
]}

MURGA, J ^{[1
]}

GONZALEZ, F ^{[1
]}

MARCO, JA ^{[1
]}

机构：

[1] UNIV VALENCIA,DEPT QUIM ORGAN,E-46100 BURJASSOT,SPAIN

来源：

TETRAHEDRON | 1995年 / 51卷 / 09期

关键词：

D O I：

10.1016/0040-4020(95)00025-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of the title compounds in optically active form from geraniol as the starting material is described. The physical and spectral properties of the synthetic amide are identical with those of the natural compound acacialactam, this fact confirming that the structure proposed for the latter compound is not correct. The configuration of the single stereogenic carbon atom in the natural amide is shown to be S.

引用

收藏

页码：2755 / 2762

页数：8

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