REGIOSELECTIVE SYNTHESES OF 3-AMINOMETHYL-5-SUBSTITUTED ISOXAZOLES - A FACILE AND CHEMOSELECTIVE REDUCTION OF AZIDE TO AMINE BY SODIUM-BOROHYDRIDE USING 1,3-PROPANEDITHIOL AS A CATALYST

被引：43

作者：

PEI, YZ

WICKHAM, BOS

机构：

[1] Chiron Corporation, Emeryville, CA 94608

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 47期

关键词：

REGIOSELECTIVE SYNTHESIS; ISOXAZOLES; CATALYTIC REDUCTION; AZIDE; SODIUM BOROHYDRIDE; 1,3-PROPANEDITIOL;

D O I：

10.1016/S0040-4039(00)60386-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of isoxazole azides were reduced selectively to isoxazole amines in quantitative yield by sodium borohydride using 1,3-propanedithiol as a catalyst.

引用

页码：7509 / 7512

页数：4

共 12 条

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