THE SYNTHESIS OF A C-1-C-8 LACTONE FRAGMENT OF DISCODERMOLIDE

被引：42

作者：

GOLEC, JMC

JONES, SD

机构：

[1] Roussel Laboratories Ltd., Covingham Swindon, Wiltshire SN3 5BZ England, Kingfisher Drive

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(00)61479-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The assymetric synthesis of a fragment corresponding to the C-1-C-8 region of the immunosuppressant dicodermolide is reported. A trihydroxylactone of defined absolute stereochemistry is also prepared. This compound is a potential reductive ozonolysis product of discodermolide and may aid the determination of the absolute stereochemistry or the natural product

引用

页码：8159 / 8162

页数：4

共 8 条

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