DETERMINATION OF FUMONISINS USING ONLINE LIQUID-CHROMATOGRAPHY COUPLED TO ELECTROSPRAY MASS-SPECTROMETRY

被引：22

作者：

DOERGE, DR ^{[1
]}

HOWARD, PC ^{[1
]}

BAJIC, S ^{[1
]}

PREECE, S ^{[1
]}

机构：

[1] FISONS INSTRUMENTS ORGAN ANAL,ALTRINCHAM WA14 5RZ,CHESHIRE,ENGLAND

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1994年 / 8卷 / 08期

关键词：

D O I：

10.1002/rcm.1290080807

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Fumonisin (FB) mycotoxins are produced by Fusarium monoliforme, which grows primarily on yellow corn. Ingestion of FB1-contaminated food causes leukoencephalomalacia in horses, pulmonary edema in pigs, and is suspected in the etiology of human esophageal cancer. Chromatographic separation and detection of underivatized fumonisins has been hampered because these compounds are nonvolatile, thermally labile, and devoid of chromophoric functional groups. We report here a simple liquid chromatography/mass spectrometry method employing chromatographic separation on a polymer-based column coupled with sensitive detection using positive-ion electrospray mass spectrometry for the quantification of fumonisins B1, B2 and B3 in extracts of commercial corn meal.

引用

页码：603 / 606

页数：4

共 17 条

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