STRUCTURAL STUDIES OF THE CAPSULAR POLYSACCHARIDE OF KLEBSIELLA TYPE-33

被引:35
作者
LINDBERG, B [1 ]
LINDH, F [1 ]
LONNGREN, J [1 ]
NIMMICH, W [1 ]
机构
[1] UNIV ROSTOCK,INST MED MIKROBIOL & EPIDEMIOL,DDR-25 ROSTOCK 1,GER DEM REP
关键词
D O I
10.1016/S0008-6215(00)83277-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The structure of the capsular polysaccharide from Klebsiella type 33 has been investigated. Methylation analysis, various specific degradations, graded hydrolysis with acid, and n.m.r. spectroscopy were,the principal methods used. It is concluded that the polysaccharide is composed of pentasaccharide repeating-units having the following structure. {A figure is presented} The D-galactopyranosyl group, with pyruvic acid linked as a ketal to O-3 and O-4, was degraded on treatment of the fully methylated polysaccharide with strong base. It is proposed that methyl pyruvate is eliminated, in an E2 type of reaction. © 1979.
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页码:135 / 144
页数:10
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