REGULATION OF MATERNAL INSULIN-LIKE GROWTH-FACTOR-I BY PLACENTAL GROWTH-HORMONE IN PREGNANCY - POSSIBLE ACTION OF MATERNAL IGF-I ON FETAL GROWTH

被引：33

作者：

CAUFRIEZ, A

FRANKENNE, F

HENNEN, G

COPINSCHI, G

机构：

[1] FREE UNIV BRUSSELS, DEPT ENDOCRINOL, BRUSSELS, BELGIUM

[2] FREE UNIV BRUSSELS, DEPT OBSTET & GYNAECOL, BRUSSELS, BELGIUM

[3] UNIV LIEGE, DEPT CLIN & EXPTL ENDOCRINOL, LIEGE, BELGIUM

来源：

HORMONE RESEARCH | 1994年 / 42卷 / 1-2期

关键词：

INSULIN-LIKE GROWTH-FACTOR 1; PLACENTAL GROWTH HORMONE; PREGNANCY;

D O I：

10.1159/000184147

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In normal and in pathological human pregnancies, a specific placental growth hormone variant, rather than placental lactogen, substitutes for the suppressed pituitary GH to stimulate the maternal insulin-like growth factor I (IGF-I). In pathological pregancies with disorders of the feto-placental unit, low levels of placental GH hormone result in relatively low levels of maternal IGF-I. In normal pregnancies, the baby birth weight is positively correlated with maternal IGF-I values.

引用

收藏

页码：62 / 65

页数：4

相关论文

共 14 条

[1] REGULATION OF MATERNAL IGF-I BY PLACENTAL GH IN NORMAL AND ABNORMAL HUMAN PREGNANCIES [J].

CAUFRIEZ, A ;

FRANKENNE, F ;

HENNEN, G ;

COPINSCHI, G .

AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 265 (04) :E572-E577

[2] PLACENTAL GROWTH-HORMONE AS A POTENTIAL REGULATOR OF MATERNAL IGF-I DURING HUMAN-PREGNANCY [J].

CAUFRIEZ, A ;

FRANKENNE, F ;

ENGLERT, Y ;

GOLSTEIN, J ;

CANTRAINE, F ;

HENNEN, G ;

COPINSCHI, G .

AMERICAN JOURNAL OF PHYSIOLOGY, 1990, 258 (06) :E1014-E1019

[3] GROWTH-HORMONE 24-H SERUM PROFILES DURING PREGNANCY - LACK OF PULSATILITY FOR THE SECRETION OF THE PLACENTAL VARIANT [J].

ERIKSSON, L ;

FRANKENNE, F ;

EDEN, S ;

HENNEN, G ;

VONSCHOULTZ, B .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1989, 96 (08) :949-953

[4] THE PHYSIOLOGY OF GROWTH-HORMONES (GHS) IN PREGNANT-WOMEN AND PARTIAL CHARACTERIZATION OF THE PLACENTAL GH VARIANT [J].

FRANKENNE, F ;

CLOSSET, J ;

GOMEZ, F ;

SCIPPO, ML ;

SMAL, J ;

HENNEN, G .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1988, 66 (06) :1171-1180

[5] EXPRESSION OF THE GROWTH-HORMONE VARIANT GENE IN HUMAN-PLACENTA [J].

FRANKENNE, F ;

RENTIERDELRUE, F ;

SCIPPO, ML ;

MARTIAL, J ;

HENNEN, G .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 64 (03) :635-637

[6] SERUM IMMUNOREACTIVE SOMATOMEDIN-C IS ELEVATED LATE IN PREGNANCY [J].

FURLANETTO, RW ;

UNDERWOOD, LE ;

VANWYK, JJ ;

HANDWERGER, S .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1978, 47 (03) :695-698

[7] SERUM LEVELS OF SOMATOMEDINS AND SOMATOMEDIN-BINDING PROTEIN IN PREGNANT-WOMEN WITH TYPE-I OR GESTATIONAL DIABETES AND THEIR INFANTS [J].

HALL, K ;

HANSSON, U ;

LUNDIN, G ;

LUTHMAN, M ;

PERSSON, B ;

POVOA, G ;

STANGENBERG, M ;

OFVERHOLM, U .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 63 (06) :1300-1306

[8] OVINE PLACENTAL LACTOGEN INDUCES SOMATOMEDIN - POSSIBLE ROLE IN FETAL GROWTH [J].

HURLEY, TW ;

DERCOLE, AJ ;

HANDWERGER, S ;

UNDERWOOD, LE ;

FURLANETTO, RW ;

FELLOWS, RE .

ENDOCRINOLOGY, 1977, 101 (05) :1635-1638

[9] EXPRESSION AND SECRETION OF THE HUMAN PLACENTAL GROWTH-HORMONE IN ESCHERICHIA-COLI [J].

IGOUT, A ;

SCIPPO, ML ;

FRANKENNE, F ;

HENNEN, G .

NUCLEIC ACIDS RESEARCH, 1989, 17 (10) :3998-3998

[10] IMMUNOCYTOCHEMICAL LOCALIZATION OF THE HUMAN GROWTH-HORMONE VARIANT IN THE HUMAN-PLACENTA [J].

JARA, CS ;

SALUD, AT ;

BRYANTGREENWOOD, GD ;

PIRENS, G ;

HENNEN, G ;

FRANKENNE, F .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1989, 69 (05) :1069-1072