The effects on bone cells of metal ions released from orthopaedic implants. A review

被引：304

作者：

Sansone, Valerio ^{[1
]}

Pagani, Davide ^{[1
]}

Melato, Marco ^{[1
]}

机构：

[1] Univ Milan, Ist Ortoped Galeazzi IRCCS, Dept Orthopaed, Via Galeazzi,4, I-20161 Milan, Italy

来源：

CLINICAL CASES IN MINERAL AND BONE METABOLISM | 2013年 / 10卷 / 01期

关键词：

orthopaedic implants; metal ions; adverse effects; bone cells; osteolysis;

D O I：

10.11138/ccmbm/2013.10.1.034

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

The increasing use of orthopedic implants and, in particular, of hip and knee joint replacements for young and active patients, has stimulated interest and concern regarding the chronic, long-term effects of the materials used. This review focuses on the current knowledge of the adverse biologic reactions to metal particles released from orthopaedic implants in vivo and in vitro. More specifically, the purpose of this article is to provide an overview of the current literature about the adverse effects of metal particles on bone cells and peri-implant bone.

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收藏

页码：34 / 40

页数：7

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