ACUTE TOXOPLASMA MYOSITIS - AN IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL-STUDY

被引：13

作者：

MATSUBARA, S ^{[1
]}

TAKAMORI, M ^{[1
]}

ADACHI, H ^{[1
]}

KIDA, H ^{[1
]}

机构：

[1] NATL KANAZAWA HOSP, DEPT INTERNAL MED, KANAZAWA, JAPAN

来源：

ACTA NEUROPATHOLOGICA | 1990年 / 81卷 / 02期

关键词：

MYOSITIS; TOXOPLASMOSIS; MACROPHAGES; LYMPHOCYTES-T; MAJOR HISTOCOMPATIBILITY COMPLEX;

D O I：

10.1007/BF00334513

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The occurrence is reported of acute myositis in a man with meningoencephalitis due to toxoplasmosis. The ultrastructure and immunohistochemistry of a muscle biopsy of the patient were investigate. Toxoplasma organisms were not found in the muscle biopsy. The perivascular inflammatory cells in the muscle were mainly CD4+ T cells and the inflammatory cells in and around the muscle fibres were chiefly macrophages. Expression of major histocompatibility complex class I and II antigens was observed in the infiltrating cells and endothelial cells of the blood vessels. A small proportion of the infiltrating cells expressed interferon-gamma. A possible role of the immune mechanism in the evolution of myositis is discussed.

引用

页码：223 / 227

页数：5