HEPOXILINS-B-3 - SYNTHESIS OF ALL 4 STEREOISOMERS AND A GLUTATHIONE ADDUCT

被引：10

作者：

BELOSLUDTSEV, YY

KOLLAH, RO

FALCK, JR

CAPDEVILA, JH

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT MOLEC GENET,DALLAS,TX 75235

[2] UNIV TEXAS,SW MED CTR,DEPT PHARMACOL,DALLAS,TX 75235

[3] VANDERBILT UNIV,SCH MED,DEPT MED,NASHVILLE,TN 37205

[4] VANDERBILT UNIV,SCH MED,DEPT BIOCHEM,NASHVILLE,TN 37205

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 30期

关键词：

EICOSANOID; (-)QUINIC ACID; EPOXY-ALCOHOL; WITTIG; OXIRANYL-CARBINOL;

D O I：

10.1016/S0040-4039(00)73491-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Utilizing (-)-quinic acid as a differentiated bis-aldehyde chiron, both pairs of hepoxilin B-3 enantiomers and a glutathione adduct were synthesized by regiospecific functionalization of an acyclic vic-diol.

引用

页码：5327 / 5330

页数：4

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