TOTAL SYNTHESIS OF 12-(S)-10-HYDROXY-TRANS-11,12-EPOXYEICOSA-5,9,14-(Z)-TRIENOIC ACIDS, METABOLITES OF ARACHIDONIC-ACID IN MAMMALIAN BLOOD-PLATELETS

被引：32

作者：

COREY, EJ ^{[1
]}

KANG, J ^{[1
]}

LAGUZZA, BC ^{[1
]}

JONES, RL ^{[1
]}

机构：

[1] UNIV EDINBURGH,DEPT PHARMACOL,EDINBURGH EH8 9J2,SCOTLAND

来源：

TETRAHEDRON LETTERS | 1983年 / 24卷 / 45期

关键词：

D O I：

10.1016/S0040-4039(01)99809-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：4913 / 4916

页数：4

共 12 条

[1] ISOLATION OF A NEW LIPOXYGENASE METABOLITE OF ARACHIDONIC-ACID, 8,11,12-TRIHYDROXY-5,9,14-EICOSATRIENOIC ACID FROM HUMAN PLATELETS [J].

BRYANT, RW ;

BAILEY, JM .

PROSTAGLANDINS, 1979, 17 (01) :9-18

[2] TOTAL SYNTHESIS OF 5S,12S-DIHYDROXY-6,10-E,8,14-Z-EICOSATETRAENOIC ACID (5S,12S-DI-HETE) (2), A NEW HUMAN METABOLITE OF ARACHIDONIC-ACID [J].

COREY, EJ ;

MARFAT, A ;

LAGUZZA, BC .

TETRAHEDRON LETTERS, 1981, 22 (35) :3339-3342

[3] SIMPLE SYNTHESIS OF THE 11,12-OXIDO AND 14,15-OXIDO ANALOGS OF LEUKOTRIENE-A AND THE CORRESPONDING CONJUGATES WITH GLUTATHIONE AND CYSTEINYLGLYCINE, ANALOGS OF LEUKOTRIENE-C AND LEUKOTRIENE-D [J].

COREY, EJ ;

MARFAT, A ;

GOTO, G .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (21) :6607-6608

[4] H-1 NMR-STUDY OF CONVERSION OF 13(S)-HYDROPEROXY LINOLEIC-ACID BY SOYA BEAN LIPOXYGENASE-I [J].

EGMOND, MR ;

WILLIAMS, RJP .

BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 531 (02) :141-148

[5] FORMATION OF THREO-11-HYDROXY-TRANS-12=13-EPOXY-9-CIS-OCTADECENOIC ACID BY ENZYMIC ISOMERIZATION OF 13-L-HYDROPEROXY-9-CIS,11-TRANS-OCTADECADIENOIC ACID BY SOYBEAN LIPOXYGENASE-1 [J].

GARSSEN, GJ ;

VELDINK, GA ;

VLIEGENTHART, JFG ;

BOLDINGH, J .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1976, 62 (01) :33-36

[6] PROSTAGLANDIN ENDOPEROXIDES - NOVEL TRANSFORMATIONS OF ARACHIDONIC-ACID IN HUMAN PLATELETS [J].

HAMBERG, M ;

SAMUELSS.B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (09) :3400-3404

[7] NEW REACTION OF UNSATURATED FATTY-ACID HYDROPEROXIDES - FORMATION OF 11-HYDROXY-12,13-EPOXY-9-OCTADECENOIC ACID FROM "13-HYDROPEROXY-9,11-OCTADECADIENOIC ACID [J].

HAMBERG, M ;

GOTTHAMMAR, B .

LIPIDS, 1973, 8 (12) :737-744

[8] IDENTIFICATION OF TRIHYDROXYEICOSATRIENOIC ACIDS AS PRODUCTS FROM INCUBATION OF ARACHIDONIC-ACID WITH WASHED BLOOD-PLATELETS [J].

JONES, RL ;

KERRY, PJ ;

POYSER, NL ;

WALKER, IC ;

WILSON, NH .

PROSTAGLANDINS, 1978, 16 (04) :583-589

[9] STIMULATION OF LEUKOTRIENE BIOSYNTHESIS IN HUMAN-BLOOD LEUKOCYTES BY PLATELET-DERIVED 12-HYDROPEROXY-ICOSATETRAENOIC ACID [J].

MACLOUF, J ;

DELACLOS, BF ;

BORGEAT, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (19) :6042-6046

[10] ESSENTIAL FATTY ACIDS .1. SYNTHESIS OF LINOLEIC, GAMMA-LINOLENIC, ARACHIDONIC, AND DOCOSA-4,7,10,13,16-PENTAENOIC ACID [J].

OSBOND, JM ;

PHILPOTT, PG ;

WICKENS, JC .

JOURNAL OF THE CHEMICAL SOCIETY, 1961, (JUL) :2779-&

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