DIMERIC APORPHINE-BENZYLISOQUINOLINE AND APORPHINE-PAVINE ALKALOIDS

被引:26
作者
GUINAUDEAU, H [1 ]
LEBOEUF, M [1 ]
CAVE, A [1 ]
机构
[1] FAC MED & PHARM BESANCON, F-25030 BESANCON, FRANCE
来源
LLOYDIA-THE JOURNAL OF NATURAL PRODUCTS | 1979年 / 42卷 / 02期
关键词
D O I
10.1021/np50002a001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Aporphine-benzylisoquinoline dimers represent a small group of alkaloids; they have been found only in three genera, Thalidrum (Ranunculaceae), Hernandia (Hernandiaceae) and Berberis (Berberidaceae). At the present time, only two dimeric aporphine-pavine alkaloids have been found in Thalidrum. The first aporphine-benzylisoquinoline alkaloid to be fully characterized was thalicarpine by Kupchan (13) in 1963. The dimeric alkaloids found in the genus Thalidrum have been discussed in reviews on Thalidrum alkaloids by Schiff and Doskotch (34) in 1970, Mollov el al. (17) in 1971 and Tomimatsu (35) in 1965, 1967 and 1976. At the present time, more than 20 dimeric alkaloids are known. © 1979, American Chemical Society. All rights reserved.
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页码:133 / 149
页数:17
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