IMMUNOHISTOCHEMICAL DEMONSTRATION OF INSULIN-LIKE GROWTH FACTOR-I (IGF-1) IN NORMAL AND PATHOLOGICAL HUMAN PITUITARY-GLANDS

被引:23
作者
ALBERTI, VN [1 ]
TAKITA, LC [1 ]
DEMESQUITA, MIS [1 ]
PERCARIO, S [1 ]
MACIEL, RMB [1 ]
机构
[1] ESCOLA PAULISTA MED SCH,DEPT MED,BR-04023 SAO PAULO,BRAZIL
关键词
GROWTH FACTORS; IGF-1; PITUITARY IMMUNOHISTOCHEMISTRY;
D O I
10.1016/S0344-0338(11)80138-X
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The authors have studied the presence and distribution of Insulin-Like-Growth-Factor-1 (IGF-1) in 5 autopsied normal and 20 surgically removed human pituitary adenomas, employing a peroxidase-anti-peroxidase method. IGF-1 could be demonstrated in all cases, with variation of cells immunostaining from 60% in normal pituitary gland to 100% in corticotroph cell adenoma.
引用
收藏
页码:541 / 542
页数:2
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