IMMUNOHISTOCHEMICAL DEMONSTRATION OF INSULIN-LIKE GROWTH FACTOR-I (IGF-1) IN NORMAL AND PATHOLOGICAL HUMAN PITUITARY-GLANDS

被引：23

作者：

ALBERTI, VN ^{[1
]}

TAKITA, LC ^{[1
]}

DEMESQUITA, MIS ^{[1
]}

PERCARIO, S ^{[1
]}

MACIEL, RMB ^{[1
]}

机构：

[1] ESCOLA PAULISTA MED SCH,DEPT MED,BR-04023 SAO PAULO,BRAZIL

来源：

PATHOLOGY RESEARCH AND PRACTICE | 1991年 / 187卷 / 05期

关键词：

GROWTH FACTORS; IGF-1; PITUITARY IMMUNOHISTOCHEMISTRY;

D O I：

10.1016/S0344-0338(11)80138-X

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The authors have studied the presence and distribution of Insulin-Like-Growth-Factor-1 (IGF-1) in 5 autopsied normal and 20 surgically removed human pituitary adenomas, employing a peroxidase-anti-peroxidase method. IGF-1 could be demonstrated in all cases, with variation of cells immunostaining from 60% in normal pituitary gland to 100% in corticotroph cell adenoma.

引用

页码：541 / 542

页数：2