MUTATIONAL STUDIES WITH DIQUAT AND PARAQUAT INVITRO

被引：27

作者：

BENIGNI, R ^{[1
]}

BIGNAMI, M ^{[1
]}

CARERE, A ^{[1
]}

CONTI, G ^{[1
]}

CONTI, L ^{[1
]}

CREBELLI, R ^{[1
]}

DOGLIOTTI, E ^{[1
]}

GUALANDI, G ^{[1
]}

NOVELLETTO, A ^{[1
]}

ORTALI, VA ^{[1
]}

机构：

[1] UNIV ROME,I-00100 ROME,ITALY

来源：

MUTATION RESEARCH | 1979年 / 68卷 / 03期

关键词：

D O I：

10.1016/0165-1218(79)90148-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Diquat and paraquat were assayed in the following tests. (1) Ames test in Salmonella typhimurium (strains TA1535, TA1537, TA1538, TA98 and TA100) with and without rat-liver microsomal fractions. (2) Resistance to 8-azaguanine in Salmonella typhimurium (strain hisG46, TA92 and TA1535. (3) Repair test in Salmonella typhimurium (strains TA1538 and TA1978). (4) Gene mutations in Aspergillus nidulans: 8-AG resistance and methionine suppression (meth A1 locus). (5) Lethal recessive damage in Aspergillus nidulans. (6) Unscheduled DNA synthesis (UDS) in human epithelial-like cells (EUE). Diquat and paraquat were positive in S. typhimurium (in the repair test and the 8-AG resistance system), in A. nidulans (for gene mutations and lethal recessive damage induction) and in EUE cells (UDS induction). © 1979.

引用

页码：183 / 193

页数：11

共 40 条

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