STRUCTURE-ACTIVITY STUDIES OF 20-DEOXO-20-AMINO DERIVATIVES OF TYLOSIN-RELATED MACROLIDES

被引：20

作者：

KIRST, HA

WILLARD, KE

DEBONO, M

TOTH, JE

TRUEDELL, BA

LEEDS, JP

OTT, JL

FELTYDUCKWORTH, AM

COUNTER, FT

OSE, EE

CROUSE, GD

TUSTIN, JM

OMURA, S

机构：

[1] ELI LILLY INT CORP,GREENFIELD,IN 46140

[2] KITASATO UNIV,SCH PHARMACEUT SCI,TOKYO 108,JAPAN

[3] KITASATO INST,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1989年 / 42卷 / 11期

关键词：

D O I：

10.7164/antibiotics.42.1673

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1673 / 1683

页数：11

共 16 条

[1] CYANOHYDRIDOBORATE ANION AS A SELECTIVE REDUCING AGENT [J].

BORCH, RF ;

BERNSTEIN, MD ;

DURST, HD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (12) :2897-+

[2] SYNTHESIS AND ANTIMICROBIAL EVALUATION OF 20-DEOXO-20-(3,5-DIMETHYLPIPERIDIN-1-YL)DESMYCOSIN (TILMICOSIN, EL-870) AND RELATED CYCLIC AMINO DERIVATIVES [J].

DEBONO, M ;

WILLARD, KE ;

KIRST, HA ;

WIND, JA ;

CROUSE, GD ;

TAO, EV ;

VICENZI, JT ;

COUNTER, FT ;

OTT, JL ;

OSE, EE ;

OMURA, S .

JOURNAL OF ANTIBIOTICS, 1989, 42 (08) :1253-1267

[3] SYNTHESIS AND EVALUATION OF TYLOSIN-RELATED MACROLIDES MODIFIED AT THE ALDEHYDE FUNCTION - A NEW SERIES OF ORALLY EFFECTIVE ANTIBIOTICS [J].

KIRST, HA ;

TOTH, JE ;

DEBONO, M ;

WILLARD, KE ;

TRUEDELL, BA ;

OTT, JL ;

COUNTER, FT ;

FELTYDUCKWORTH, AM ;

PEKAREK, RS .

JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (08) :1631-1641

[4] INVITRO AND INVIVO EVALUATION OF C-20-MODIFIED AND C-23-MODIFIED DERIVATIVES OF TYLOSIN AGAINST VETERINARY PATHOGENS [J].

KIRST, HA ;

OSE, EE ;

TOTH, JE ;

WILLARD, KE ;

DEBONO, M ;

FELTYDUCKWORTH, AM ;

PEKAREK, RS .

JOURNAL OF ANTIBIOTICS, 1988, 41 (07) :938-948

[5] STRUCTURE-ACTIVITY STUDIES AMONG 16-MEMBERED MACROLIDE ANTIBIOTICS RELATED TO TYLOSIN [J].

KIRST, HA ;

WILD, GM ;

BALTZ, RH ;

HAMILL, RL ;

OTT, JL ;

COUNTER, FT ;

OSE, EE .

JOURNAL OF ANTIBIOTICS, 1982, 35 (12) :1675-1682

[6] FUSOBACTERIUM-NECROPHORUM - ITS CHARACTERISTICS AND ROLE AS AN ANIMAL PATHOGEN [J].

LANGWORTH, BF .

BACTERIOLOGICAL REVIEWS, 1977, 41 (02) :373-390

[7] CHEMICAL MODIFICATION OF TYLOSIN - SYNTHESIS OF AMINO DERIVATIVES AT C-20 POSITION OF TYLOSIN AND DEMYCAROSYLTYLOSIN [J].

MATSUBARA, H ;

INOKOSHI, J ;

NAKAGAWA, A ;

TANAKA, H ;

OMURA, S .

JOURNAL OF ANTIBIOTICS, 1983, 36 (12) :1713-1721

[8] NOVEL DIMERIC DERIVATIVES OF LEUCOMYCINS AND TYLOSIN, 16-MEMBERED MACROLIDES [J].

OMURA, S ;

MIYANO, K ;

MATSUBARA, H ;

NAKAGAWA, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (03) :271-275

[9] INVITRO ANTIBACTERIAL PROPERTIES OF EL-870, A NEW SEMISYNTHETIC MACROLIDE ANTIBIOTIC [J].

OSE, EE .

JOURNAL OF ANTIBIOTICS, 1987, 40 (02) :190-194

[10] SINGLE-DOSE TREATMENT OF NEONATAL CALF PNEUMONIA WITH THE NEW MACROLIDE ANTIBIOTIC TILMICOSIN [J].

OSE, EE ;

TONKINSON, LV .

VETERINARY RECORD, 1988, 123 (14) :367-369

← 1 2 →