Structure and mitogenic activities of corn cob heteroxylans

被引：66

作者：

Ebringerova, A ^{[1
]}

Hromadkova, Z ^{[1
]}

Hribalova, V ^{[1
]}

机构：

[1] NATL INST PUBL HLTH, CR-10042 PRAGUE, CZECH REPUBLIC

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 1995年 / 17卷 / 06期

关键词：

heteroxylans; xylan derivatives; immunomodulators; mitogenic and co-mitogenic activity;

D O I：

10.1016/0141-8130(96)81840-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Various structurally different water-soluble (ws) and water-insoluble (wis) heteroxylans have been tested for mitogenic and co-mitogenic activity and shown to differ in their stimulating potency. The ws arabinoglucuronoxylan (ws-AGX) from corn cobs exhibited the highest potency which was comparable to that of the immunomodulator zymosan, whereas the wis-AGX from corn cobs was inactive. Water-soluble derivatives of wis-AGX as well as hydrolytically modified ws-AGX fractions were prepared and tested for their mitogenic and co-mitogenic activity. The results indicate that the disaccharide side chains present only in ws-AGX might be important for expression of the immunostimulatory activity of this xylan.

引用

页码：327 / 331

页数：5

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