THE IMPORTANT ROLE OF ALBUMIN IN DETERMINING THE RELATIVE HUMAN BLOOD STABILITIES OF THE CAMPTOTHECIN ANTICANCER DRUGS

被引：100

作者：

BURKE, TG ^{[1
]}

MUNSHI, CB ^{[1
]}

MI, ZH ^{[1
]}

JIANG, Y ^{[1
]}

机构：

[1] OHIO STATE UNIV,CTR COMPREHENS CANC,COLUMBUS,OH 43210

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1995年 / 84卷 / 04期

关键词：

D O I：

10.1002/jps.2600840426

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：518 / 519

页数：2

共 14 条

[1]

Burke SR, 1980, COMPOSITION FUNCTION

[2] LIPID BILAYER PARTITIONING AND STABILITY OF CAMPTOTHECIN DRUGS [J].

BURKE, TG ;

MISHRA, AK ;

WANI, MC ;

WALL, ME .

BIOCHEMISTRY, 1993, 32 (20) :5352-5364

[3] LIPOSOMAL STABILIZATION OF CAMPTOTHECINS LACTONE RING [J].

BURKE, TG ;

STAUBUS, AE ;

MISHRA, AK ;

MALAK, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (21) :8318-8319

[4] PREFERENTIAL BINDING OF THE CARBOXYLATE FORM OF CAMPTOTHECIN BY HUMAN SERUM-ALBUMIN [J].

BURKE, TG ;

MI, ZH .

ANALYTICAL BIOCHEMISTRY, 1993, 212 (01) :285-287

[5] ETHYL SUBSTITUTION AT THE 7-POSITION EXTENDS THE HALF-LIFE OF 10-HYDROXYCAMPTOTHECIN IN THE PRESENCE OF HUMAN SERUM-ALBUMIN [J].

BURKE, TG ;

MI, Z .

JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (17) :2580-2582

[6]

BURKE TG, 1993, J MED CHEM, V37, P40

[7]

HSIANG YH, 1985, J BIOL CHEM, V260, P4873

[8]

JAXEL C, 1989, CANCER RES, V49, P5077

[9] DIFFERENTIAL INTERACTIONS OF CAMPTOTHECIN LACTONE AND CARBOXYLATE FORMS WITH HUMAN BLOOD COMPONENTS [J].

MI, ZH ;

BURKE, TG .

BIOCHEMISTRY, 1994, 33 (34) :10325-10336

[10] MARKED INTERSPECIES VARIATIONS CONCERNING THE INTERACTIONS OF CAMPTOTHECIN WITH SERUM ALBUMINS - A FREQUENCY-DOMAIN FLUORESCENCE SPECTROSCOPIC STUDY [J].

MI, ZH ;

BURKE, TG .

BIOCHEMISTRY, 1994, 33 (42) :12540-12545

← 1 2 →