NONFIBROUS DUST LOAD AND SMOKING IN DENTAL-TECHNICIANS - A STUDY USING BRONCHOALVEOLAR LAVAGE

被引:7
作者
BERNSTEIN, M
PAIRON, JC
MORABIA, A
GAUDICHET, A
JANSON, X
BROCHARD, P
机构
[1] LAB ETUD PARTICULES,F-75013 PARIS,FRANCE
[2] HOP HENRI MONDOR,INSERM,U139,F-94010 CRETEIL,FRANCE
关键词
D O I
10.1136/oem.51.1.23
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A study was conducted with transmission electron microscopy to find whether bronchoalveolar lavage could be used to identify subjects with occupational exposure to mineral particles. Non-fibrous mineral particles in bronchoalveolar lavage (BAL) fluid from 46 dental technicians and 41 white collar controls with lung diseases but free from occupational exposure to dusts were analysed. The total particle concentration in BAL fluid was significantly higher in dental technicians than in controls (12.18 x 10(5) particles/ml of BAL fluid, v 2.03 x 10(5) particles/ml, p < 0.001). Dental technicians had significantly more crystalline silica, aluminium, and alloys containing nickel and chromium. There was a non-significant twofold increase of total particle concentration in the lungs of dental technicians who were smokers compared with non-smokers. The results strongly support the use of BAL fluid analysis to assess dust accumulation in workers in heavily exposed occupations such as dental technicians. This is a valid method to evaluate occupational exposure to non-fibrous mineral particles, and may be useful to determine the occupational aetiology of some respiratory diseases.
引用
收藏
页码:23 / 27
页数:5
相关论文
共 25 条
[11]  
DEVUYST P, 1987, EUR J RESPIR DIS, V70, P150
[12]  
GAUDICHET A, 1987, REV MAL RESPIR, V4, P237
[13]  
GAUDICHET A, 1978, REV FR MAL RESPIR, V6, P345
[14]   IDENTIFICATION OF INORGANIC DUST PARTICLES IN BRONCHOALVEOLAR LAVAGE MACROPHAGES BY ENERGY DISPERSIVE-X-RAY MICROANALYSIS [J].
JOHNSON, NF ;
HASLAM, PL ;
DEWAR, A ;
NEWMANTAYLOR, AJ ;
TURNERWARWICK, M .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1986, 41 (03) :133-144
[15]  
LIEBLING RS, 1971, ENVIRON LETT, V2, P153
[16]  
MAIER EA, 1986, CLIN CHEM, V32, P551
[17]   MORPHOLOGY AND PATHOGENESIS OF PNEUMOCONIOSIS IN DENTAL-TECHNICIANS [J].
MORGENROTH, K ;
KRONENBERGER, H ;
MICHALKE, G ;
SCHNABEL, R .
PATHOLOGY RESEARCH AND PRACTICE, 1985, 179 (4-5) :528-536
[18]  
PARKES WR, 1982, OCCUPATIONAL LUNG DI
[19]  
PELTIER A, 1979, INRS PUBLICATION, V3, P166
[20]   PNEUMOCONIOSIS AND EXPOSURES OF DENTAL LABORATORY TECHNICIANS [J].
ROM, WN ;
LOCKEY, JE ;
LEE, JS ;
KIMBALL, AC ;
BANG, KM ;
LEAMAN, H ;
JOHNS, RE ;
PERROTA, D ;
GIBBONS, HL .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1984, 74 (11) :1252-1257