LECTIN COATED PIEZOELECTRIC CRYSTAL BIOSENSORS

被引：15

作者：

BARNES, C

DSILVA, C

JONES, JP

LEWIS, TJ

机构：

[1] University of Wales, Bangor, Institute of Molecular and Biomolecular Electronics, School of Electronic Engineering Science, Bangor, Gwynedd LL57 1UT, Dean Street

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 1992年 / 7卷 / 1-3期

关键词：

D O I：

10.1016/0925-4005(92)80322-O

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The lectins Helix pomatia and Ptilota plumosa have been covalently immobilised on the surfaces of silver electroded AT-cut quartz crystals to form sugar and erythrocyte specific sensors. Using fully immersed crystals the dissociation constant for the Helix pomatia-n-acetyl D-galactosamine complex has been found to be typically 1.2 mM. A microdelivery mode has also been investigated and using this mode the dissociation constant for Ptilota plumosa with D-galactose was found to be approximately 7 mM. The lower detection limit for erythrocytes was of the order of 10(3) cells.

引用

页码：347 / 350

页数：4

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