BIOACTIVE AND OTHER SESQUITERPENOIDS FROM PORELLA-CORDEANA

被引：55

作者：

HARRIGAN, GG ^{[1
]}

AHMAD, A ^{[1
]}

BAI, N ^{[1
]}

GLASS, TE ^{[1
]}

GUNATILAKA, AAL ^{[1
]}

KINGSTON, DGI ^{[1
]}

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV,DEPT CHEM,BLACKSBURG,VA 24061

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 06期

关键词：

D O I：

10.1021/np50096a016

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Bioassay-directed fractionation of the MeCOEt extract of Porella cordeana yielded drimenin [1] and aristolone [4], which were moderately toxic towards DNA-repair-deficient mutants of Saccharomyces cerevisiae. Three inactive sesquiterpenes, 7-ketoisodrimenin [2],7-ketoisodrimenin-5-ene [3], and norpinguisanolide, were also obtained. Compounds 2 and 3 are new.

引用

页码：921 / 925

页数：5

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