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NOVEL ISOXAZOLES WHICH INTERACT WITH BRAIN CHOLINERGIC CHANNEL RECEPTORS HAVE INTRINSIC COGNITIVE ENHANCING AND ANXIOLYTIC ACTIVITIES

被引：99
作者：
GARVEY, DS
WASICAK, JT
DECKER, MW
BRIONI, JD
BUCKLEY, MJ
SULLIVAN, JP
CARRERA, GM
HOLLADAY, MW
ARNERIC, SP
WILLIAMS, M
机构：
[1] Neuroscience Research Division, Pharmaceutical Discovery, Abbott Laboratories, Illinois 60064, D-47W, AP-10, Abbott Park
[2] Anti-infective Research Division
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1994年 / 37卷 / 08期
关键词：
D O I：
10.1021/jm00034a002
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：1055 / 1059
页数：5
相关论文
共 51 条
  • [41] RINNE JO, 1991, BRAIN RES, V547, P167
  • [42] THE EFFECTS OF NICOTINE ON ATTENTION, INFORMATION-PROCESSING, AND SHORT-TERM-MEMORY IN PATIENTS WITH DEMENTIA OF THE ALZHEIMER TYPE
    SAHAKIAN, B
    JONES, G
    LEVY, R
    GRAY, J
    WARBURTON, D
    [J]. BRITISH JOURNAL OF PSYCHIATRY, 1989, 154 : 797 - 800
  • [43] THE DIVERSITY OF NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS
    SARGENT, PB
    [J]. ANNUAL REVIEW OF NEUROSCIENCE, 1993, 16 : 403 - 443
  • [44] NICOTINIC CHOLINERGIC RECEPTOR-BINDING SITES IN THE BRAIN - REGULATION INVIVO
    SCHWARTZ, RD
    KELLAR, KJ
    [J]. SCIENCE, 1983, 220 (4593) : 214 - 216
  • [45] CHANGES IN NICOTINIC AND MUSCARINIC CHOLINERGIC RECEPTORS IN ALZHEIMER-TYPE DEMENTIA
    SHIMOHAMA, S
    TANIGUCHI, T
    FUJIWARA, M
    KAMEYAMA, M
    [J]. JOURNAL OF NEUROCHEMISTRY, 1986, 46 (01) : 288 - 293
  • [46] PRE-SYNAPTIC CHOLINERGIC DYSFUNCTION IN PATIENTS WITH DEMENTIA
    SIMS, NR
    BOWEN, DM
    ALLEN, SJ
    SMITH, CCT
    NEARY, D
    THOMAS, DJ
    DAVISON, AN
    [J]. JOURNAL OF NEUROCHEMISTRY, 1983, 40 (02) : 503 - 509
  • [47] REDUCTIONS IN [H-3] NICOTINIC ACETYLCHOLINE BINDING IN ALZHEIMERS-DISEASE AND PARKINSONS-DISEASE - AN AUTORADIOGRAPHIC STUDY
    WHITEHOUSE, PJ
    MARTINO, AM
    WAGSTER, MV
    PRICE, DL
    MAYEUX, R
    ATACK, JR
    KELLAR, KJ
    [J]. NEUROLOGY, 1988, 38 (05) : 720 - 723
  • [48] NICOTINIC ACETYLCHOLINE BINDING-SITES IN ALZHEIMERS-DISEASE
    WHITEHOUSE, PJ
    MARTINO, AM
    ANTUONO, PG
    LOWENSTEIN, PR
    COYLE, JT
    PRICE, DL
    KELLAR, KJ
    [J]. BRAIN RESEARCH, 1986, 371 (01) : 146 - 151
  • [49] WHITING P, 1991, MOL PHARMACOL, V40, P463
  • [50] WORMSLEY KG, 1978, GASTROENTEROLOGY, V75, P139
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