ENANTIOMERIZATION OF 2,2'-DIISOPROPYLBIPHENYL DURING CHIRAL INCLUSION GAS-CHROMATOGRAPHY - DETERMINATION OF THE ROTATIONAL ENERGY BARRIER BY COMPUTER-SIMULATION OF DYNAMIC CHROMATOGRAPHIC ELUTION PROFILES

被引：42

作者：

JUNG, M ^{[1
]}

FLUCK, M ^{[1
]}

SCHURIG, V ^{[1
]}

机构：

[1] UNIV TUBINGEN,INST ORGAN CHEM,D-72076 TUBINGEN,GERMANY

来源：

CHIRALITY | 1994年 / 6卷 / 06期

关键词：

2,2'-DIISOPROPYLBIPHENYL; RACEMIZATION AND ENANTIOMERIZATION; ROTATIONAL ENERGY BARRIER; COMPUTER SIMULATION; DYNAMIC CHIRAL GAS CHROMATOGRAPHY; CYCLODEXTRIN STATIONARY PHASE;

D O I：

10.1002/chir.530060610

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

By computer simulation of experimental dynamic gas chromatographic elution profiles, the rotational energy barrier Delta G(=) of racemic 2,2'-diisopropylbiphenyl has been determined as 114.6-115.0 kJ/mol (75-100 degrees C). These data are in good agreement with a value that was determined previously by measuring the racemization kinetics of an enriched sample. This indicates that there is no measurable catalytic or inhibitory effect of the stationary phase. (C) 1994 Wiley-Liss, Inc.

引用

页码：510 / 512

页数：3

共 12 条

[1] DYNAMIC PHENOMENA DURING ENANTIOMER RESOLUTION BY COMPLEXATION GAS-CHROMATOGRAPHY - A KINETIC-STUDY OF ENANTIOMERIZATION [J].