The spatial localization of Dlx-2 during tooth development

被引：28

作者：

Thomas, BL

Porteus, MH

Rubenstein, JLR

Sharpe, PT

机构：

[1] UMDS,GUYS HOSP,DEPT CRANIOFACIAL DEV,LONDON,ENGLAND

[2] UNIV CALIF SAN FRANCISCO,LANGLEY PORTER PSYCHIAT INST,SAN FRANCISCO,CA 94143

[3] UNIV CALIF SAN FRANCISCO,DEPT PSYCHIAT,SAN FRANCISCO,CA 94143

来源：

CONNECTIVE TISSUE RESEARCH | 1995年 / 32卷 / 1-4期

关键词：

Dlx-2; homeobox; toothgerm; development;

D O I：

10.3109/03008209509013702

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The spatial distribution of Dlx-2 protein during murine tooth development has been investigated using immunohistochemistry with Dlx-2 antibodies. In common with several other homeobox genes expressed in toothgerms, Dlx-2 shows a multiphasic distribution in both epithelially and mesenchymally derived structures. This localization shows a number of similarities with the expression of Msx-2 and suggests a role for Dlx-2 in tooth initiation and tissue patterning.

引用

页码：27 / 34

页数：8

共 26 条

[1] THE MOUSE DLX-2 (TES-1) GENE IS EXPRESSED IN SPATIALLY RESTRICTED DOMAINS OF THE FOREBRAIN, FACE AND LIMBS IN MIDGESTATION MOUSE EMBRYOS [J].