DETECTION OF NASOPHARYNGEAL CARCINOMA USING TC-99(M) METHOXYISOBUTYLISONITRILE SPECT

被引:31
作者
KAO, CH
WANG, SJ
LIN, WY
HSU, CY
LIAO, SQ
YEH, SH
机构
[1] Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung Taiwan, 40705, 160 Taichung Harbor Road
关键词
D O I
10.1097/00006231-199301000-00009
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Tc-99m-methoxyisobutylisonitrile (MIBI) single photon emission computed tomography (SPECT) of the head and neck was performed in 20 patients with nasopharyngeal carcinoma (NPC) to detect the malignancies. Ten volunteers also underwent Tc-99m-MIBI SPECT of the head and neck for comparison. The results showed no MIBI uptake in the nasopharynx of any of the 10 normal volunteers. In the patients with NPC, 6/20 (30%) of the cases had no MIBI uptake in the nasopharynx and 14/20 (70%) had increased MIBI uptake in the nasopharynx. In addition, three cases with cervical metastases were detected by Tc-99m-MIBI. However, MIBI uptake in the NPC was not related to the size or differentiation of the NPC.
引用
收藏
页码:41 / 46
页数:6
相关论文
共 28 条
[11]  
Sehweil A.M., McKillop J.H., Milroy R., Et al., Mechanism of Tl-201 uptake in tumors, Eur J Nucl Med, 15, (1989)
[12]  
Ohta H., Endo K., Fujita T., Et al., Imaging of head and neck tumors with technetium(V)-99m DMSA - a new tumor- seeking agent, Clin Nucl Med, 10, (1985)
[13]  
Piwnica-Worms D., Kronauge J.F., Chiu M.L., Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium (I) in cultured chick myocardial cells. Mitochondrial and plasma membrane potential dependence, Circulation, 82, (1990)
[14]  
Beller G.A., Watson D.D., Physiological basis of myocardial perfusion imaging with the technetium 99m agents, Sem Nucl Med, 21, (1991)
[15]  
Aktolun C., Bayhan H., Metin K., Et al., Clinical experience with Tc-99m MIBI imaging in patients with malignant tumors: Preliminary results and comparison with Tl-201, Clin Nucl Med, 17, (1992)
[16]  
Hassan I.M., Sehweil A., Constantinides C., Et al., Uptake and kinetics of Tc-99m hexakis 2-methoxy isobutyl isonitrile in benign and malignant lesions in the lungs, Clin Nucl Med, 14, (1989)
[17]  
O'driscoll C.M., Baker F., Casey M.J., Duffy G.J., Localization of recurrent medullary thyroid carcinomas with technetium-99m-methoxyisobutylnitrile scintigraphy: A case report, J Nucl Med, (1991)
[18]  
Mueller S.P., Piotrowski B., Guth-Tougelides B., Reiners C., Tc-99m MIBI and Tl-201 uptake in thyroid carcinoma, J Nucl Med, 29, (1988)
[19]  
O'tuama L.A., Packard A.B., Treves S.T., SPECT imaging of pediatric brain tumor with hexakis (Methyoxyisobutyliso-nitrile) technetium (I), J Nucl Med, (1990)
[20]  
Caner B., Kitapci M., Unlu M., Et al., Techr a-99m-MIBI uptake in benign and malignant bone le a comparative study with technetium-99m-MDP, J Nucl Med, 33, (1992)