CLONING OF A HUMAN CDNA-ENCODING A PUTATIVE NUCLEOTIDE-BINDING PROTEIN RELATED TO ESCHERICHIA-COLI MIND

被引：10

作者：

SHAHRESTANIFAR, M

SAHA, DP

SCALA, LA

BASU, A

HOWELLS, RD

机构：

[1] UNIV MED & DENT NEW JERSEY,NEW JERSEY MED SCH,DEPT BIOCHEM & MOLEC BIOL,NEWARK,NJ 07103

[2] UNIV MED & DENT NEW JERSEY,GRAD SCH BIOMED SCI,NEWARK,NJ 07103

来源：

GENE | 1994年 / 147卷 / 02期

关键词：

NUCLEOTIDE-BINDING DOMAIN; MINB OPERON; CELL DIVISION; ATPASE; ATP-BINDING SITE; NEUROBLASTOMA; POLYMERASE CHAIN REACTION;

D O I：

10.1016/0378-1119(94)90082-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A novel human cDNA encoding a putative nucleotide-binding protein (NBP) was obtained by screening a human SHSY5Y neuroblastoma library. The deduced protein contains 320 amino acids (aa) with a M(r) of 34 540. NBP displays sequence similarity with the product of the minD gene from Escherichia coli. MinD is involved in the proper placement of the division septum, and has ATPase activity. NBP and MinD contain consensus nucleotide (nt)-binding domains. The NBP mRNA is approx. 1500 nt in length and is expressed in several human cell lines and in all rat tissues examined, with the highest levels in lung and testis.

引用

页码：281 / 285

页数：5

共 20 条

[1] SEQUENCE IDENTIFICATION OF 2,375 HUMAN BRAIN GENES [J].