DIFFERENCES IN RED-CELL MEMBRANE-PROTEINS IN RHESUS-MONKEY ERYTHROCYTES

被引：2

作者：

BALLAS, SK ^{[1
]}

GOODMAN, AM ^{[1
]}

STOLL, DB ^{[1
]}

机构：

[1] CASE WESTERN RESERVE UNIV, CLEVELAND METROPOLITAN GEN HOSP, DIV HEMATOL, CLEVELAND, OH 44109 USA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1981年 / 68卷 / 03期

关键词：

D O I：

10.1016/0305-0491(81)90150-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Red cell membranes were isolated from rhesus-monkey erythrocytes and their proteins were analyzed by polyacrylamide gel electrophoresis in sodium dodecyl sulfate and compared to the membrane protein pattern of human red cells. Rhesus-monkey erythrocytes had a significantly different distribution of spectrin-binding proteins. Specifically, they lacked band 2.2, had relatively greater amounts of bands 2.3 and 4.2 and had less protein in band 4.1. Whereas band 3 in human red cell membranes is a wide and diffuse region, in the rhesus monkey it is a discrete and narrow band suggesting a greater degree of homogeneity. The low MW polypeptides; i.e., band 6, the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase, and bands 7-8, were significantly decreased in comparison to their human counterparts.

引用

页码：421 / 423

页数：3