COMPARISON OF THE EFFECTS OF ETHANE-1-HYDROXY-1,1-DIPHOSPHONATE AND DICHLOROMETHYLENE DIPHOSPHONATE UPON PERIODONTAL BONE-RESORPTION IN RICE RATS (ORYZOMYS-PALUSTRIS)

被引：10

作者：

LEONARD, EP

REESE, WV

MANDEL, EJ

机构：

[1] Naval Dental Research Institute, Naval Base, Great Lakes, IL 60088

来源：

ARCHIVES OF ORAL BIOLOGY | 1979年 / 24卷 / 09期

关键词：

D O I：

10.1016/0003-9969(79)90122-5

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Young male rice rats maintained on a powdered diet were treated for 10 days with either ethane-1-hydroxy-1,1-diphosphonate (EHDP) or dichloromethylene diphosphonate (Cl2MDP) at a dose of 4 mg/kg body weight. Cl2MDP-recipients displayed significantly less alveolar bone loss than EHDP-recipients (p < 0.05) or control animals (p < 0.01) when examined 2 weeks after the treatment. © 1979.

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页码：707 / 708

页数：2

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