AN ASYMMETRIC-SYNTHESIS OF ISOPODOPHYLLOTOXIN

被引：28

作者：

PELTER, A ^{[1
]}

WARD, RS ^{[1
]}

LI, QR ^{[1
]}

PIS, J ^{[1
]}

机构：

[1] UNIV COLL SWANSEA,DEPT CHEM,SWANSEA SA2 8PP,W GLAM,WALES

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(00)86243-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(-)-Isopodophyllotoxin has been synthesised by a route involving an asymmetric Diels Alder reaction between (5R)-menthyloxy-2(5H)-furanone and an arylisobenzofuran. Raney nickel reduction of the major adduct affords 10-menthyloxyisopicropodophyllin which is converted into (-)-isopodophyllotoxin.

引用

页码：909 / 920

页数：12

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