SOME STATISTICAL ASPECTS OF LOW-DOSE ELECTRON IMAGING OF CRYSTALS

被引：6

作者：

BRILLINGER, DR

DOWNING, KH

GLAESER, RM

机构：

[1] UNIV CALIF BERKELEY,DEPT STAT,BERKELEY,CA 94720

[2] UNIV CALIF BERKELEY LAWRENCE BERKELEY LAB,DONNER LAB,BERKELEY,CA 94720

[3] UNIV CALIF BERKELEY,DEPT BIOPHYS,BERKELEY,CA 94720

来源：

JOURNAL OF STATISTICAL PLANNING AND INFERENCE | 1990年 / 25卷 / 03期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

Combination of images; convergence factors; crystallography; density estimation; error analysis; Fourier analysis; Fourier synthesis; image processing; noise images;

D O I：

10.1016/0378-3758(90)90075-6

中图分类号：

O21 [概率论与数理统计]; C8 [统计学];

学科分类号：

020208 ; 070103 ; 0714 ;

摘要：

The concern is with improving images of molecular structures obtained by biophysicists employing electron microscopes. The phases obtained by Fourier transforming electron micrographs are combined with available more precise amplitudes, in a Fourier synthesis, to obtain images. A study is made of the merits of various multipliers (convergence factors) employed in the Fourier synthesis. An estimate of the error of the improved image is constructed. A method of combining images from different experiments is developed. A noise corrupted version of a high-resolution two-dimensional image of bacteriorhodopsin is employed to visually and formally assess the relative merits of different multipliers. © 1990.

引用

页码：235 / 259

页数：25

共 15 条

[11] PROJECTED STRUCTURE OF PURPLE MEMBRANE DETERMINED TO 3.7 A RESOLUTION BY LOW-TEMPERATURE ELECTRON-MICROSCOPY [J].