GLYCOPEPTIDOLIPIDS - A NEW CLASS OF ARTIFICIAL ANTIGENS WITH CARBOHYDRATE DETERMINANTS - SYNTHESIS OF ARTIFICIAL ANTIGEN WITH TYPE-SPECIFIC OLIGOSACCHARIDE HAPTEN FROM NEISSERIA-MENINGITIDIS GROUP-B

被引：3

作者：

DMITRIEV, BA

OVCHINNIKOV, MV

LAPINA, EB

PLUZHNIKOVA, GN

LOPYREV, IV

CHERNYAK, AY

机构：

[1] CARDIOL RES CTR, MOSCOW 121552, USSR

[2] ND ZELINSKII ORGAN CHEM INST, MOSCOW 117913, USSR

来源：

GLYCOCONJUGATE JOURNAL | 1992年 / 9卷 / 04期

关键词：

LIPOOLIGOSACCHARIDE; LIPOPEPTIDE; GLYCOPEPTIDOLIPID; ARTIFICIAL ANTIGEN;

D O I：

10.1007/BF00731161

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synthetic lipopeptide N-palmitoyltyrosyl-seryl-seryl-asparaginyl-alanine, an analogue of B-mitogenic tripalmitoyl-pentapeptide from Escherichia coli lipoprotein, was coupled with an oligosaccharide hapten from Neisseria meningitidis lipooligosaccharide to give a glycopeptidolipid conjugate - the artificial antigen of a new type possessing the type-specific microbial determinant.

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页码：168 / 173

页数：6

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