MOLECULAR MECHANISMS OF DIURETIC AGENTS

被引：16

作者：

BREYER, J

JACOBSON, HR

机构：

[1] Department of Medicine, Vanderbilt University Medical Center, Nashville

来源：

ANNUAL REVIEW OF MEDICINE | 1990年 / 41卷

关键词：

Carbonic anhydrase inhibitors; Furosemide; Ion transport; Thiazides;

D O I：

10.1146/annurev.me.41.020190.001405

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Recent identification of the renal epithelial cell ion transporters inhibited by diuretics allows physicians to select appropriate types and doses of diuretics. The desirable and undesirable clinical consequences of these molecular mechanisms of action can also be predicted.

引用

收藏

页码：265 / 275

页数：11

相关论文

共 45 条

[31] COMPARISON OF LOCAL EFFECTS OF AMILORIDE HYDROCHLORIDE ON ISOTONIC FLUID ABSORPTION IN DISTAL AND PROXIMAL CONVOLUTED TUBULE [J].

MENG, K .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1975, 357 (1-2) :91-99

[32] MECHANISM OF NACL AND WATER REABSORPTION IN PROXIMAL CONVOLUTED TUBULE OF RAT-KIDNEY - ROLE OF CHLORIDE CONCENTRATION GRADIENTS [J].

NEUMANN, KH ;

RECTOR, FC .

JOURNAL OF CLINICAL INVESTIGATION, 1976, 58 (05) :1110-1118

[33] RENAL TUBULAR SECRETION AND EFFECTS OF THE ALKALINE DIURETICS AMILORIDE, TIZOLEMIDE (HOE-740) AND 2-AMINOMETHYL-4-(1,1-DIMETHYLETHYL)-6-IODOPHENOL HYDROCHLORIDE (MK-447) [J].

ODLIND, B .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1981, 317 (04) :357-363

[34]

ODLIND B, 1979, J PHARMACOL EXP THER, V211, P238

[35] NA-K-2CL COTRANSPORT IN WINTER FLOUNDER INTESTINE AND BOVINE KIDNEY OUTER MEDULLA - [H-3] BUMETANIDE BINDING AND EFFECTS OF FUROSEMIDE ANALOGS [J].

OGRADY, SM ;

PALFREY, HC ;

FIELD, M .

JOURNAL OF MEMBRANE BIOLOGY, 1987, 96 (01) :11-18

[36]

Palmer L G, 1981, Ann N Y Acad Sci, V372, P1, DOI 10.1111/j.1749-6632.1981.tb15453.x

[37] MECHANISM OF BICARBONATE REABSORPTION IN PROXIMAL AND DISTAL TUBULES OF KIDNEY [J].

RECTOR, FC ;

CARTER, NW ;

SELDIN, DW .

JOURNAL OF CLINICAL INVESTIGATION, 1965, 44 (02) :278-+

[38] EFFECT OF HIGH CEILING DIURETICS ON ACTIVE SALT TRANSPORT IN THE CORTICAL THICK ASCENDING LIMB OF HENLE LOOP OF RABBIT KIDNEY - CORRELATION OF CHEMICAL-STRUCTURE AND INHIBITORY POTENCY [J].

SCHLATTER, E ;

GREGER, R ;

WEIDTKE, C .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1983, 396 (03) :210-217

[39] SODIUM-CHLORIDE ABSORPTION BY THE URINARY-BLADDER OF THE WINTER FLOUNDER - A THIAZIDE-SENSITIVE, ELECTRICALLY NEUTRAL TRANSPORT-SYSTEM [J].

STOKES, JB ;

LEE, I ;

DAMICO, M .

JOURNAL OF CLINICAL INVESTIGATION, 1984, 74 (01) :7-16

[40] MINERALOCORTICOID MODULATION OF RABBIT MEDULLARY COLLECTING DUCT ACIDIFICATION - A SODIUM-INDEPENDENT EFFECT [J].

STONE, DK ;

SELDIN, DW ;

KOKKO, JP ;

JACOBSON, HR .

JOURNAL OF CLINICAL INVESTIGATION, 1983, 72 (01) :77-83

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