SIMULTANEOUS DETERMINATION OF ACETAMINOPHEN AND CAFFEINE IN TABLET PREPARATIONS BY PARTIAL LEAST-SQUARES MULTIVARIATE SPECTROPHOTOMETRIC CALIBRATION

被引：43

作者：

BOZDOGAN, A

ACAR, AM

KUNT, GK

机构：

[1] Yildiz University, Department of Chemistry, Şişli, Istanbul

来源：

TALANTA | 1992年 / 39卷 / 08期

关键词：

D O I：

10.1016/0039-9140(92)80281-H

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The use of partial least-squares spectrophotometric calibration for the simultaneous determination of analgesic tablets in a multicomponent formulation is presented. This method is applied to the determination of acetaminophen and caffeine in tablet preparations. The results show that these components in a molar ratio of about 21:1 in tablets have been determined simultaneously with high precision.

引用

页码：977 / 979

页数：3