DETECTION OF THE MARINE TOXINS OKADAIC ACID AND DOMOIC ACID IN SHELLFISH AND PHYTOPLANKTON IN THE GULF OF MEXICO

被引：49

作者：

DICKEY, RW ^{[1
]}

FRYXELL, GA ^{[1
]}

GRANADE, HR ^{[1
]}

ROELKE, D ^{[1
]}

机构：

[1] TEXAS A&M UNIV SYST,COLL GEOSCI,DEPT OCEANOG,COLLEGE STN,TX 77843

来源：

TOXICON | 1992年 / 30卷 / 03期

关键词：

D O I：

10.1016/0041-0101(92)90877-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Liquid chromatographic analyses of extracts from shellfish and phytoplankton from the Gulf of Mexico indicated the presence of the marine toxins okadaic acid (0.162-mu-g/g shellfish) and domoic acid (2.1 pg/cell phytoplankter). These toxins are causative agents of diarrhetic shellfish poisoning (DSP) and amnesic shellfish poisoning (ASP), respectively. The presence of DSP and ASP toxins in a region with no previous record of outbreaks may indicate a potential for human poisoning under conditions appropriate for accumulation of these toxins in shellfish.

引用

页码：355 / 359

页数：5

共 9 条

[1] IDENTIFICATION OF OKADAIC ACID FROM A CARIBBEAN DINOFLAGELLATE, PROROCENTRUM-CONCAVUM [J].

DICKEY, RW ;

BOBZIN, SC ;

FAULKNER, DJ ;

BENCSATH, FA ;

ANDRZEJEWSKI, D .

TOXICON, 1990, 28 (04) :371-377

[2]

FRYXELL GA, 1990, NOVA HEDWIGIA S, V100, P171

[3]

LEE JS, 1987, AGR BIOL CHEM TOKYO, V51, P881

[4] TRACE DETERMINATION OF DOMOIC ACID IN SEAWATER AND PHYTOPLANKTON BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF THE FLUORENYLMETHOXYCARBONYL (FMOC) DERIVATIVE [J].

POCKLINGTON, R ;

MILLEY, JE ;

BATES, SS ;

BIRD, CJ ;

DEFREITAS, ASW ;

QUILLIAM, MA .

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 1990, 38 (03) :351-368

[5] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF DOMOIC ACID, A MARINE NEUROTOXIN, WITH APPLICATION TO SHELLFISH AND PLANKTON [J].

QUILLIAM, MA ;

SIM, PG ;

MCCULLOCH, AW ;

MCINNES, AG .

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 1989, 36 (03) :139-154

[6]

WEKELL MM, 1991, J ASSOC OFF ANA CHEM, V74, P139

[7] IDENTIFICATION OF DOMOIC ACID, A NEUROEXCITATORY AMINO-ACID, IN TOXIC MUSSELS FROM EASTERN PRINCE-EDWARD-ISLAND [J].

WRIGHT, JLC ;

BOYD, RK ;

DEFREITAS, ASW ;

FALK, M ;

FOXALL, RA ;

JAMIESON, WD ;

LAYCOCK, MV ;

MCCULLOCH, AW ;

MCINNES, AG ;

ODENSE, P ;

PATHAK, VP ;

QUILLIAM, MA ;

RAGAN, MA ;

SIM, PG ;

THIBAULT, P ;

WALTER, JA ;

GILGAN, M ;

RICHARD, DJA ;

DEWAR, D .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1989, 67 (03) :481-490

[8] DIARRHETIC SHELLFISH TOXINS [J].

YASUMOTO, T ;

MURATA, M ;

OSHIMA, Y ;

SANO, M ;

MATSUMOTO, GK ;

CLARDY, J .

TETRAHEDRON, 1985, 41 (06) :1019-1025

[9]

YASUMOTO T, 1978, B JPN SOC SCI FISH, V44, P1249

← 1 →