Small actin-binding proteins: the beta-thymosin family

被引：108

作者：

Nachmias, Vivianne T. ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Dept Cell & Dev Biol, Philadelphia, PA 19104 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 01期

关键词：

D O I：

10.1016/S0955-0674(05)80008-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Thymosin beta(4) is a major actin monomer binding protein present at high concentration in many vertebrate cells and cell lines. The interactions of actin with thymosin beta(4), actobindin and profilin are compared. Nine beta-thymosins have been identified; six have been shown to bind to actin. Regulation of the synthesis of thymosin beta(10) and thymosin beta(4) has been found in brain development and after stimulation of several cell types, respectively. The extracellular effects of thymosin beta(4) still need clarification.

引用

页码：56 / 62

页数：7

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