ARTERIAL-WALL OR PLASMA-RENIN IN HYPERTENSION

被引：119

作者：

SWALES, JD ^{[1
]}

机构：

[1] UNIV LEICESTER, DEPT MED, LEICESTER LE1 7RH, ENGLAND

来源：

CLINICAL SCIENCE | 1979年 / 56卷 / 04期

关键词：

D O I：

10.1042/cs0560293

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Local generation of angiotensin II by renin-like activity within the resistance vessel walls is important both in maintaining blood pressure and in determining pressor sensitivity to exogenous angiotensin. Such renin-like activity is biochemically similar to, if not identical with, renal renin and is probably derived from the kidney. It has a much longer half-life than plasma renin. The renin-angiotensin system thus probably functions as a local humoral control system within the blood vessel wall.

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页码：293 / 298

页数：6

相关论文

共 47 条

[1] INHIBITION OF CONVERTING ENZYME OF RENIN-ANGIOTENSIN SYSTEM IN KIDNEYS AND HINDLEGS OF DOGS [J].

AIKEN, JW ;

VANE, JR .

CIRCULATION RESEARCH, 1972, 30 (03) :263-&

[2] PARTIAL CHARACTERIZATION OF AORTIC RENIN IN SPONTANEOUSLY HYPERTENSIVE RAT AND ITS INTERRELATIONSHIP WITH PLASMA-RENIN, BLOOD-PRESSURE AND SODIUM BALANCE [J].

BARRETT, JD ;

EGGENA, P ;

SAMBHI, MP .

CLINICAL SCIENCE AND MOLECULAR MEDICINE, 1978, 55 (03) :261-270

[3]

BASSO N, 1971, ACTA PHYSIOL LAT AM, V21, P8

[4]

BING J, 1973, ACTA PATH MICRO IM A, VA 81, P247

[5]

BROWN JJ, 1976, LANCET, V1, P1219

[6] ANGIOTENSIN-II VASCULAR RECEPTORS - THEIR AVIDITY IN RELATIONSHIP TO SODIUM BALANCE, AUTONOMIC NERVOUS-SYSTEM, AND HYPERTENSION [J].

BRUNNER, HR ;

CHANG, P ;

WALLACH, R ;

SEALEY, JE ;

LARAGH, JH .

JOURNAL OF CLINICAL INVESTIGATION, 1972, 51 (01) :58-+

[7] ESTIMATING RENIN PARTICIPATION IN HYPERTENSION - SUPERIORITY OF CONVERTING ENZYME-INHIBITOR OVER SARALASIN [J].

CASE, DB ;

WALLACE, JM ;

KEIM, HJ ;

WEBER, MA ;

DRAYER, JIM ;

WHITE, RP ;

SEALEY, JE ;

LARAGH, JH .

AMERICAN JOURNAL OF MEDICINE, 1976, 61 (05) :790-796

[8] RESPONSE OF BLOOD-PRESSURE TO INFUSION OF ANGIOTENSIN-II - RELATION TO PLASMA CONCENTRATIONS OF RENIN AND ANGIOTENSIN-II [J].

CHINN, RH ;

DUSTERDIECK, G .

CLINICAL SCIENCE, 1972, 42 (04) :489-+

[9] COMPARISON OF EFFECTS OF LOCALLY INFUSED ANGIOTENSIN-I AND ANGIOTENSIN-II ON HAND VEINS AND FOREARM ARTERIES IN MAN - EVIDENCE FOR CONVERTING ENZYME-ACTIVITY IN LIMB VESSELS [J].

COLLIER, JG ;

ROBINSON, BF .

CLINICAL SCIENCE AND MOLECULAR MEDICINE, 1974, 47 (02) :189-192

[10] UNTERSCHIEDLICHE BEEINFLUSSUNG DER BLUTDRUCKWIRKUNG VON RENIN UND ANGIOTENSIN DURCH AMINOPEPTIDASE [J].

DAUM, A ;

UEHLEKE, H ;

KLAUS, D .

NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE, 1966, 254 (04) :327-&

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