A NEW AND EASY ROUTE TO (2E,4E)-DIENALS BY 4-CARBON HOMOLOGATION OF ALDEHYDES

被引：14

作者：

BELLASSOUED, M

SALEMKOUR, M

机构：

[1] Laboratoire de Synthèse Organométallique associè au CNRS, Université Pierre et Marie Curie, 75252 Paris Cedex 05, 4, Place Jussieu

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 33期

关键词：

D O I：

10.1016/S0040-4039(00)73973-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthetic method of (2E,4E)-dienals by four-carbon homologation of aldehydes is described. gamma-trimethylsilyl crotonaldimine 2 , easily generated from N-ter-butyl-crotonaldimine 1, LDA and ClSiMe3, reacts with aldehydes in the presence of catalytic CsF in DMSO at rt --> 100-degrees-C to afford homologous aldehydes 3 in good yields and with excellent (E,E)-selectivities.

引用

页码：5281 / 5284

页数：4