REACTIONS OF PROTECTED AMINO-ACID CHLORIDES MEDIATED BY SMI2

被引：15

作者：

COLLIN, J ^{[1
]}

NAMY, JL ^{[1
]}

JONES, G ^{[1
]}

KAGAN, HB ^{[1
]}

机构：

[1] UNIV PARIS 11,INST CHIM MOLEC ORSAY,CNRS,SYNTH ASYMETR LAB,F-91405 ORSAY,FRANCE

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 21期

关键词：

SAMARIUM DIIODIDE; AMINO-ACID CHLORIDES; AMINOALCOHOLS; KETONES; ALDEHYDES; DECARBONYLATION;

D O I：

10.1016/S0040-4039(00)79575-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reactions of N-protected amino acid chlorides with carbonyl compounds in the presence of SmI2 were investigated. Decarbonylation followed by a cross coupling between amino moiety and aldehyde or ketone is observed. By the use of FMOC derivatives, N-protected amino alcohols were isolated in moderate yields.

引用

页码：2973 / 2976

页数：4

共 15 条

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