ORAL AND PHARYNGEAL CANCER, DIET, SMOKING, ALCOHOL, AND SERUM VITAMIN-A AND BETA-CAROTENE LEVELS - A CASE-CONTROL STUDY IN MEN

被引:44
作者
KUNE, GA
KUNE, S
FIELD, B
WATSON, LF
CLELAND, H
MERENSTEIN, D
VITETTA, L
机构
来源
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL | 1993年 / 20卷 / 01期
关键词
D O I
10.1080/01635589309514271
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A case-control study was conducted in Melbourne, Australia. Forty-one men with histologically confirmed squamous cell oral or pharyngeal cancer were compared with 398 male community controls. A statistically significant increase in risk was found for alcohol (ethanol) consumption and for smoking, and there was a synergistic effect for these two exposures. Statistically significant protection was noted with increasing intake of dietary vitamin C, dietary beta-carotene, fruit, vegetables, and dietary fiber. The mean serum levels of beta-carotene and vitamin A were statistically significantly lower when the cases were compared with another set of 88 male controls of a similar age who were hospitalized for minor surgical operations. This study confirms a causal effect of smoking and alcohol and a protective role for a high dietary intake of fruit, vegetables, cereals, and, particularly, beta-carotene- and vitamin C-containing foods.
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页码:61 / 70
页数:10
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