HELICAL NICKEL(II) COMPLEXES AS MOBILE PHASE ADDITIVES IN THE REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF ALKYLAMINE ENANTIOMERS

被引：12

作者：

BAZYLAK, G

机构：

来源：

ANALYST | 1992年 / 117卷 / 09期

关键词：

CHIRAL SEPARATION; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; NICKEL(II) SQUARE-PLANAR COMPLEXES; DIAMINE SYNTHESIS; ALKYLAMINE ENANTIOMER SEPARATION;

D O I：

10.1039/an9921701429

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The addition of nickel(II) chelates of tetradentate Schiff bases differing slightly in molecular structure to a water-acetonitrile (80 + 20) mobile phase in reversed-phase high-performance liquid chromatography makes it possible to perform enantiomeric and diastereoisomeric separations of aliphatic mono- and diamines. The separation was achieved on an octadecylsilane stationary phase without derivatization of the starting amine, and the results were compared with those obtained by a gas chromatographic procedure. The influence of helical structure, hydrophobicity, concentration and adsorption of the chelates present in the chromatographic system on the separation of the solutes studied is discussed.

引用

页码：1429 / 1433

页数：5

共 38 条

[1] COPPER(II) COMPLEXES OF DIAMINO-DIAMIDO-TYPE LIGANDS AS CHIRAL ELUENTS IN THE ENANTIOMERIC SEPARATION OF D,L-DANSYLAMINO ACIDS BY REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].